WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_SCGGAAGY_V$ELK1_02       ID:DB_ID:2413
C=1176; O=18; E=3.46; R=5.20; rawP=1.21e-08; adjP=2.22e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100129 NA EIF3L eukaryotic translation initiation factor 3, subunit L 51386 ENSG00000100129
2  ENSG00000119729 NA RHOQ ras homolog family member Q 23433 ENSG00000119729
3  ENSG00000185236 NA RAB11B RAB11B, member RAS oncogene family 9230 ENSG00000185236
4  ENSG00000162191 NA UBXN1 UBX domain protein 1 51035 ENSG00000162191
5  ENSG00000102897 NA LYRM1 LYR motif containing 1 57149 ENSG00000102897
6  ENSG00000111678 NA C12orf57 chromosome 12 open reading frame 57 113246 ENSG00000111678
7  ENSG00000108953 NA YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 7531 ENSG00000108953
8  ENSG00000147677 NA EIF3H eukaryotic translation initiation factor 3, subunit H 8667 ENSG00000147677
9  ENSG00000105705 NA SUGP1 SURP and G patch domain containing 1 57794 ENSG00000105705
10  ENSG00000101384 NA JAG1 jagged 1 182 ENSG00000101384
11  ENSG00000182973 NA CNOT10 CCR4-NOT transcription complex, subunit 10 25904 ENSG00000182973
12  ENSG00000132792 NA CTNNBL1 catenin, beta like 1 56259 ENSG00000132792
13  ENSG00000132394 NA EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 60678 ENSG00000132394
14  ENSG00000141030 NA COPS3 COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) 8533 ENSG00000141030
15  ENSG00000167118 NA URM1 ubiquitin related modifier 1 81605 ENSG00000167118
16  ENSG00000135624 NA CCT7 chaperonin containing TCP1, subunit 7 (eta) 10574 ENSG00000135624
17  ENSG00000100764 NA PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 5700 ENSG00000100764
18  ENSG00000204438 NA GPANK1 G patch domain and ankyrin repeats 1 7918 ENSG00000204438


Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=28; E=8.51; R=3.29; rawP=1.86e-08; adjP=2.22e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185236 NA RAB11B RAB11B, member RAS oncogene family 9230 ENSG00000185236
2  ENSG00000165916 NA PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 5702 ENSG00000165916
3  ENSG00000115685 NA PPP1R7 protein phosphatase 1, regulatory subunit 7 5510 ENSG00000115685
4  ENSG00000162191 NA UBXN1 UBX domain protein 1 51035 ENSG00000162191
5  ENSG00000105701 NA FKBP8 FK506 binding protein 8, 38kDa 23770 ENSG00000105701
6  ENSG00000127946 NA HIP1 huntingtin interacting protein 1 3092 ENSG00000127946
7  ENSG00000181163 NA NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 4869 ENSG00000181163
8  ENSG00000108953 NA YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 7531 ENSG00000108953
9  ENSG00000103502 NA CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 10423 ENSG00000103502
10  ENSG00000147471 NA PROSC proline synthetase co-transcribed homolog (bacterial) 11212 ENSG00000147471
11  ENSG00000114784 NA EIF1B eukaryotic translation initiation factor 1B 10289 ENSG00000114784
12  ENSG00000118257 NA NRP2 neuropilin 2 8828 ENSG00000118257
13  ENSG00000105705 NA SUGP1 SURP and G patch domain containing 1 57794 ENSG00000105705
14  ENSG00000101384 NA JAG1 jagged 1 182 ENSG00000101384
15  ENSG00000167881 NA SRP68 signal recognition particle 68kDa 6730 ENSG00000167881
16  ENSG00000132394 NA EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 60678 ENSG00000132394
17  ENSG00000196419 NA XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 2547 ENSG00000196419
18  ENSG00000102103 NA PQBP1 polyglutamine binding protein 1 10084 ENSG00000102103
19  ENSG00000119048 NA UBE2B ubiquitin-conjugating enzyme E2B 7320 ENSG00000119048
20  ENSG00000065978 NA YBX1 Y box binding protein 1 4904 ENSG00000065978
21  ENSG00000157954 NA WIPI2 WD repeat domain, phosphoinositide interacting 2 26100 ENSG00000157954
22  ENSG00000135624 NA CCT7 chaperonin containing TCP1, subunit 7 (eta) 10574 ENSG00000135624
23  ENSG00000168090 NA COPS6 COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) 10980 ENSG00000168090
24  ENSG00000087191 NA PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 5705 ENSG00000087191
25  ENSG00000068697 NA LAPTM4A lysosomal protein transmembrane 4 alpha 9741 ENSG00000068697
26  ENSG00000204498 NA NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 4795 ENSG00000204498
27  ENSG00000133112 NA TPT1 tumor protein, translationally-controlled 1 7178 ENSG00000133112
28  ENSG00000128185 NA DGCR6L DiGeorge syndrome critical region gene 6-like 85359 ENSG00000128185


Database:Transcription Target       Name:hsa_RCGCANGCGY_V$NRF1_Q6       ID:DB_ID:2441
C=894; O=12; E=2.63; R=4.56; rawP=1.42e-05; adjP=0.0010
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185721 NA DRG1 developmentally regulated GTP binding protein 1 4733 ENSG00000185721
2  ENSG00000101384 NA JAG1 jagged 1 182 ENSG00000101384
3  ENSG00000170310 NA STX8 syntaxin 8 9482 ENSG00000170310
4  ENSG00000181163 NA NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 4869 ENSG00000181163
5  ENSG00000157954 NA WIPI2 WD repeat domain, phosphoinositide interacting 2 26100 ENSG00000157954
6  ENSG00000144895 NA EIF2A eukaryotic translation initiation factor 2A, 65kDa 83939 ENSG00000144895
7  ENSG00000150459 NA SAP18 Sin3A-associated protein, 18kDa 10284 ENSG00000150459
8  ENSG00000100528 NA CNIH cornichon homolog (Drosophila) 10175 ENSG00000100528
9  ENSG00000166295 NA ANAPC16 anaphase promoting complex subunit 16 119504 ENSG00000166295
10  ENSG00000087191 NA PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 5705 ENSG00000087191
11  ENSG00000130725 NA UBE2M ubiquitin-conjugating enzyme E2M 9040 ENSG00000130725
12  ENSG00000204438 NA GPANK1 G patch domain and ankyrin repeats 1 7918 ENSG00000204438


Database:Transcription Target       Name:hsa_GGAANCGGAANY_UNKNOWN       ID:DB_ID:2258
C=106; O=5; E=0.31; R=16.02; rawP=1.63e-05; adjP=0.0010
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000183207 NA RUVBL2 RuvB-like 2 (E. coli) 10856 ENSG00000183207
2  ENSG00000131100 NA ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 529 ENSG00000131100
3  ENSG00000204438 NA GPANK1 G patch domain and ankyrin repeats 1 7918 ENSG00000204438
4  ENSG00000162191 NA UBXN1 UBX domain protein 1 51035 ENSG00000162191
5  ENSG00000147677 NA EIF3H eukaryotic translation initiation factor 3, subunit H 8667 ENSG00000147677


Database:Transcription Target       Name:hsa_V$NRF2_Q4       ID:DB_ID:2287
C=252; O=6; E=0.74; R=8.09; rawP=0.0001; adjP=0.0040
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000113558 NA SKP1 S-phase kinase-associated protein 1 6500 ENSG00000113558
2  ENSG00000159352 NA PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 5710 ENSG00000159352
3  ENSG00000135862 NA LAMC1 laminin, gamma 1 (formerly LAMB2) 3915 ENSG00000135862
4  ENSG00000087191 NA PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 5705 ENSG00000087191
5  ENSG00000101210 NA EEF1A2 eukaryotic translation elongation factor 1 alpha 2 1917 ENSG00000101210
6  ENSG00000169714 NA CNBP CCHC-type zinc finger, nucleic acid binding protein 7555 ENSG00000169714


Database:Transcription Target       Name:hsa_GTGACGY_V$E4F1_Q6       ID:DB_ID:2412
C=646; O=9; E=1.90; R=4.73; rawP=0.0001; adjP=0.0040
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000205629 NA LCMT1 leucine carboxyl methyltransferase 1 51451 ENSG00000205629
2  ENSG00000137100 NA DCTN3 dynactin 3 (p22) 11258 ENSG00000137100
3  ENSG00000138785 NA INTS12 integrator complex subunit 12 57117 ENSG00000138785
4  ENSG00000113558 NA SKP1 S-phase kinase-associated protein 1 6500 ENSG00000113558
5  ENSG00000213465 NA ARL2 ADP-ribosylation factor-like 2 402 ENSG00000213465
6  ENSG00000170315 NA UBB ubiquitin B 7314 ENSG00000170315
7  ENSG00000101460 NA MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 84557 ENSG00000101460
8  ENSG00000147471 NA PROSC proline synthetase co-transcribed homolog (bacterial) 11212 ENSG00000147471
9  ENSG00000133112 NA TPT1 tumor protein, translationally-controlled 1 7178 ENSG00000133112


Database:Transcription Target       Name:hsa_CRGAARNNNNCGA_UNKNOWN       ID:DB_ID:2115
C=47; O=3; E=0.14; R=21.68; rawP=0.0004; adjP=0.0087
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114784 NA EIF1B eukaryotic translation initiation factor 1B 10289 ENSG00000114784
2  ENSG00000130725 NA UBE2M ubiquitin-conjugating enzyme E2M 9040 ENSG00000130725
3  ENSG00000133112 NA TPT1 tumor protein, translationally-controlled 1 7178 ENSG00000133112


Database:Transcription Target       Name:hsa_GCCATNTTG_V$YY1_Q6       ID:DB_ID:2459
C=419; O=7; E=1.23; R=5.67; rawP=0.0003; adjP=0.0087
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163486 NA SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 23380 ENSG00000163486
2  ENSG00000065978 NA YBX1 Y box binding protein 1 4904 ENSG00000065978
3  ENSG00000157954 NA WIPI2 WD repeat domain, phosphoinositide interacting 2 26100 ENSG00000157954
4  ENSG00000087191 NA PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 5705 ENSG00000087191
5  ENSG00000108953 NA YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 7531 ENSG00000108953
6  ENSG00000147471 NA PROSC proline synthetase co-transcribed homolog (bacterial) 11212 ENSG00000147471
7  ENSG00000127554 NA GFER growth factor, augmenter of liver regeneration 2671 ENSG00000127554


Database:Transcription Target       Name:hsa_GCTNWTTGK_UNKNOWN       ID:DB_ID:2247
C=299; O=6; E=0.88; R=6.81; rawP=0.0003; adjP=0.0087
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000127946 NA HIP1 huntingtin interacting protein 1 3092 ENSG00000127946
2  ENSG00000135624 NA CCT7 chaperonin containing TCP1, subunit 7 (eta) 10574 ENSG00000135624
3  ENSG00000170315 NA UBB ubiquitin B 7314 ENSG00000170315
4  ENSG00000111678 NA C12orf57 chromosome 12 open reading frame 57 113246 ENSG00000111678
5  ENSG00000130748 NA TMEM160 transmembrane protein 160 54958 ENSG00000130748
6  ENSG00000169714 NA CNBP CCHC-type zinc finger, nucleic acid binding protein 7555 ENSG00000169714


Database:Transcription Target       Name:hsa_TTCYRGAA_UNKNOWN       ID:DB_ID:2374
C=325; O=6; E=0.96; R=6.27; rawP=0.0004; adjP=0.0087
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000119048 NA UBE2B ubiquitin-conjugating enzyme E2B 7320 ENSG00000119048
2  ENSG00000100528 NA CNIH cornichon homolog (Drosophila) 10175 ENSG00000100528
3  ENSG00000101384 NA JAG1 jagged 1 182 ENSG00000101384
4  ENSG00000103502 NA CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 10423 ENSG00000103502
5  ENSG00000115685 NA PPP1R7 protein phosphatase 1, regulatory subunit 7 5510 ENSG00000115685
6  ENSG00000102897 NA LYRM1 LYR motif containing 1 57149 ENSG00000102897




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).